Breast Intracystic Papillary Carcinoma: An Update

Breast Intracystic Papillary Carcinoma: An Update
Julien Calderaro, Marc Espie, Juliette Duclos, Sylvie Giachetti, Delphine Wehrer, Wissam Sandid, Laurence Cahen-Doidy, Marcella Albiter, Anne Janin, Anne de Roquancourt
The Breast Journal Volume 15 Issue 6, Pages 639 - 644

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Intracystic papillary carcinoma (IPC), a breast tumor mainly occuring in the elderly, has long been considered as a variant of ductal carcinoma in situ (DCIS). This is now debated since metastatic cases have been reported.

In this study, surgical pieces of 20 IPCs were reassessed, and markers of myopepithelial layer (p63, CD10 and Smooth Muscle Actin) as well as estrogen receptors (ER) and progesterone receptors (PgR) and C-erb-B2 oncoprotein expression were systematically performed and quantified. In 10 cases, an associated unequivocal invasive component was found. In all 20 cases, no myoepithelial layer was found. Eighteen tumors were ER positive, 14 were PgR positive. Moreover, none of the tumors over-expressed C-erb-B2 oncoprotein. Therefore this study showed that in all cases of IPC there were microscopic features of invasive carcinoma despite good clinical prognostic indicators, and that precise characterization of tumors requires extensive paraffin embedding of surgical pieces

Quantitative Assessment of Radiation-Induced Fibrosis of the Breast with Tissue Compliance Meter, Palpation, and Radiological Imaging: Preliminary Res

Quantitative Assessment of Radiation-Induced Fibrosis of the Breast with Tissue Compliance Meter, Palpation, and Radiological Imaging: Preliminary Results
A. Gabriella Wernicke, Ruth Rosenblatt, Margarita Rasca, Preeti Parhar, Paul J. Christos, Andrew Fischer, Bhupesh Parashar, Dattatreyudu Nori
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The Breast Journal Volume 15 Issue 6, Pages 579 - 582

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This study is the first to explore the differences in radio-tracer uptake in the axilla in patients following BSGI and comparing the radio-tracer uptake in metasatic nodes versus extravasation of radio-tracer during injection.
The sensitivity of breast specific gamma imaging in detecting primary breast cancers has been shown, but its usefulness in the detection of axillary metastases has not been determined