Monday, 24 August 2009

Specimen Radiographs Assist in Identifying and Assessing Resection Margins of Occult Breast Carcinomas

Specimen Radiographs Assist in Identifying and Assessing Resection Margins of Occult Breast Carcinomas
Erik Scott Young, David E. Hogg, Helen Krontiras, Wanda Bernreuter, Marshall Urist, Kirby I. Bland, David C. Chhieng
The Breast Journal
Volume 15 Issue 5, Pages 521 - 523

Link to Journal

For carcinoma specimens with non-grossly identifiable lesions such as microcalcifications, difficulties may be encountered in locating these abnormalities and sampling the margins that are at risk. This is magnified in the case of skin-sparing procedures where the margin is a much greater surface area and is the operation of choice in patients with diffuse microcalcifications and/or multifocal in situ disease. The objective of this study was to determine the efficacy of specimen radiographs of mastectomy in identifying occult carcinoma associated with microcalcifications and assessing the resection margins.

The average number of tissue blocks sampled among randomly selected mastectomy specimens was 15.2 ± 5.4. There was no statistically significant difference in the number of blocks between mastectomy cases with specimen radiographs taken and those without (t-test). Our study suggests that specimen radiographs may assist in identifying occult breast carcinoma associated with microcalcifications and assessing the resection margins without increased sampling

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