Mammographic Density, Estrogen Receptor Status and Other Breast Cancer Tumor Characteristics

Mammographic Density, Estrogen Receptor Status and Other Breast Cancer Tumor Characteristics
Jane Ding, Ruth Warren, Anne Girling, Deborah Thompson, Douglas Easton
The Breast Journal 2010. 16;3;:279-289

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Mammographic density was a stronger risk factor for ER positive [OR = 2.94; 95% CI = 1.94–4.43; p < 0.001] than ER negative cancers when comparing breasts with greater than 50% dense region to those with less than 10% density. No other tumor characteristic had a significant correlation with breast density. These results suggest that mammographic percent density may be more strongly related to ER positive than ER negative breast cancer, but otherwise is a risk factor for breast cancer independent of other tumor characteristics